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Clinical Trials
Clinical Trials
INCB 18424-258: An Open Label Assessment of Safety And Efficacy Of Ruxolitinib (INCB018424) In Subjects With Primary Myelofibrosis, Post Essential Thrombocythemia-Myelofibrosis and Post Polycythemia Vera-Myelofibrosis Who Have Platelet Counts of 50 x 10(9)/L To 100 x 10(9)/ L Keywords: myelofibrosis | A Double-blind, Randomized, Placebo-controlled Phase III Study to Assess the Efficacy of recMAGE-A3 + AS15 Antigen-Specific Cancer Immunotherapeutic as Adjuvant Therapy in Patients with Resectable MAGE-A3-Positive Non-Small Cell Lung Cancer (MAGRIT: MAGE-A3 as Adjuvant Non-Small Cell LunG CancerR ImmunoTherapy) Keywords: Lung Cancer, non-small cell | A Phase I/II study to assess the safety and therapeutic effect of INCB007839 in combination with trastuzumab and vinorelbine in patients with metastatic HER2+ breast cancer Keywords: Breast Cancer, HER2+ | A Randomized, Double-Blind, Placebo-controlled Study of the JAK Inhibitor INCB018424 Tablets Administered Orally to Subjects with Primary Myelofibrosis (PMF), Post-Polycythemia Vera-Myelofibrosis (PPV-MF) or Post-Essential Thrombocythemia-Myelofibrosis (PET-MF)
(The COMFORT-I Trial INCB18424-351) Keywords: Bone Marrow Disorder, Myelofibrosis | Evaluation of Dual Energy Computed Tomography for Detection of Iron Deposition Keywords: Heart Disease, Tomography, iron deposition | JOINT PROJECT WITH GAINESVILLE RTOG 0420: A Phase II Study of Radiation Therapy Plus Low Dose Temozolomide Followed by Temozolomide Plus Irinotecan for Glioblastoma Multiforme (Jacksonville/9567 and Gainesville/3228) Keywords: Brain Tumor, Glioblastoma Multiforme, radiation therapy, chemotherapy | R 0974 (NSABP B-43): A PHASE III CLINICAL TRIAL COMPARING TRASTUZUMAB GIVEN CONCURRENTLY WITH RADIATION THERAPY AND RADIATION THERAPY ALONE FOR WOMEN WITH HER2-POSITIVE DUCTAL CARCINOMA IN SITU RESECTED BY LUMPECTOMY Keywords: Breast Cancer, Radiation | Randomized Phase 3b Study of Three Treatment Regimens in Subjects with Previously Untreated Multiple Myeloma Who Are Not Considered Candidates for High-Dose Chemotherapy and Autologous Stem Cell Transplantation: VELCADE® (Bortezomib), Thalidomide, and Dexamethasone (VTD) versus VELCADE® and Dexamethasone (VD) versus VELCADE® , Melphalan, and Prednisone (VMP) Keywords: Blood Cancer, Multiple Myeloma | RTOG 0436: A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin and Radiation for Patients with Esophageal Cancer who are Treated Without Surgery Keywords: Esophageal Cancer, chemotherapy, radiation | RTOG 0534: A Phase III Trial of Short Term Androgen Deprivation with Pelvic Lymph Node or Prostate Bed Only Radiotherapy (SPPORT) in Prostate Cancer Patients with a Rising PSA After Radical Prostatectomy Keywords: Prostate Cancer, Androgen Deprivation, Radiotherapy | RTOG 0617: A Randomized Phase III Comparison of Standard-Dose (60Gy) Versus High-Dose (74Gy) Conformal Radiotherapy with Concurrent and Consolidation Carboplatin/Paclitaxel +/- Cetuximab (IND#103444) in Patients with Stage IIIA/IIIB Non-Small Cell Lung Cancer Keywords: Lung cancer, Radiation, Chemotherapy | RTOG 0630: A PHASE II TRIAL OF IMAGE GUIDED PREOPERATIVE RADIOTHERAPY FOR PRIMARY SOFT TISSUE SARCOMAS OF THE EXTREMITY Keywords: Soft Tissue Cancer, Preoperative Radiotherapy, Sarcomas | The Use of Wisconsin Ginseng (panax quinquefolius) to Improve Cancer-Related Fatigue: A Randomized, Double-Blind, Placebo-Controlled Phase III Study Keywords: Ginseng, Fatigue, Cancer | UFPTI 0609-PC01: A Study Using Photon/Proton Beam Radiation Therapy and Chemotherapy for Unresectable Carcinoma of the Pancreas Keywords: Pancreatic Cancer, Photon therapy, Proton therapy, radiation | UFPTI 0704-PC02: A Pilot Study Using Neoadjuvant Proton Beam Radiation Therapy and Chemotherapy for Marginally Resectable Carcinoma of the Pancreas Keywords: Pancreatic Cancer | UFPTI 0803-SA02: A Pilot Study Investigating Neoadjuvant Temozolomide-based Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas Keywords: Soft Tissue Cancer, Sarcomas, Proton Chemoradiotherapy |
All Research
INCB 18424-258: An Open Label Assessment of Safety And Efficacy Of Ruxolitinib (INCB018424) In Subjects With Primary Myelofibrosis, Post Essential Thrombocythemia-Myelofibrosis and Post Polycythemia Vera-Myelofibrosis Who Have Platelet Counts of 50 x 10(9)/L To 100 x 10(9)/ L Keywords: myelofibrosis | A Double-blind, Randomized, Placebo-controlled Phase III Study to Assess the Efficacy of recMAGE-A3 + AS15 Antigen-Specific Cancer Immunotherapeutic as Adjuvant Therapy in Patients with Resectable MAGE-A3-Positive Non-Small Cell Lung Cancer (MAGRIT: MAGE-A3 as Adjuvant Non-Small Cell LunG CancerR ImmunoTherapy) Keywords: Lung Cancer, non-small cell | A Phase I/II study to assess the safety and therapeutic effect of INCB007839 in combination with trastuzumab and vinorelbine in patients with metastatic HER2+ breast cancer Keywords: Breast Cancer, HER2+ | A Phase II Study of E7389, A Halichondrin B Analog, In Patients with Advanced Non-Small Cell Lung Cancer (NSCLC), Who Progressed During or After Platinum-Based Doublet Chemotherapy Stratified for Prior Taxane Therapy Keywords: Lung cancer | A Randomized, Double-Blind, Placebo-controlled Study of the JAK Inhibitor INCB018424 Tablets Administered Orally to Subjects with Primary Myelofibrosis (PMF), Post-Polycythemia Vera-Myelofibrosis (PPV-MF) or Post-Essential Thrombocythemia-Myelofibrosis (PET-MF)
(The COMFORT-I Trial INCB18424-351) Keywords: Bone Marrow Disorder, Myelofibrosis | Connect ™ CLL: The Chronic Lymphocytic Leukemia Disease Reigstry Keywords: | Evaluation of Dual Energy Computed Tomography for Detection of Iron Deposition Keywords: Heart Disease, Tomography, iron deposition | JOINT PROJECT WITH GAINESVILLE RTOG 0420: A Phase II Study of Radiation Therapy Plus Low Dose Temozolomide Followed by Temozolomide Plus Irinotecan for Glioblastoma Multiforme (Jacksonville/9567 and Gainesville/3228) Keywords: Brain Tumor, Glioblastoma Multiforme, radiation therapy, chemotherapy | PAL-2: A pilot study of the Palliative ARNP (Advanced Registered Nurse Practitioner) Liaison Program (The PAL Program) intended to improve patients’ quality of life through targeted FACT-G driven palliative interventions Keywords: Metastasized Cancer, Resources, Palliative Care | R 0974 (NSABP B-43): A PHASE III CLINICAL TRIAL COMPARING TRASTUZUMAB GIVEN CONCURRENTLY WITH RADIATION THERAPY AND RADIATION THERAPY ALONE FOR WOMEN WITH HER2-POSITIVE DUCTAL CARCINOMA IN SITU RESECTED BY LUMPECTOMY Keywords: Breast Cancer, Radiation | Randomized Phase 3b Study of Three Treatment Regimens in Subjects with Previously Untreated Multiple Myeloma Who Are Not Considered Candidates for High-Dose Chemotherapy and Autologous Stem Cell Transplantation: VELCADE® (Bortezomib), Thalidomide, and Dexamethasone (VTD) versus VELCADE® and Dexamethasone (VD) versus VELCADE® , Melphalan, and Prednisone (VMP) Keywords: Blood Cancer, Multiple Myeloma | RTOG 0436: A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin and Radiation for Patients with Esophageal Cancer who are Treated Without Surgery Keywords: Esophageal Cancer, chemotherapy, radiation | RTOG 0534: A Phase III Trial of Short Term Androgen Deprivation with Pelvic Lymph Node or Prostate Bed Only Radiotherapy (SPPORT) in Prostate Cancer Patients with a Rising PSA After Radical Prostatectomy Keywords: Prostate Cancer, Androgen Deprivation, Radiotherapy | RTOG 0617: A Randomized Phase III Comparison of Standard-Dose (60Gy) Versus High-Dose (74Gy) Conformal Radiotherapy with Concurrent and Consolidation Carboplatin/Paclitaxel +/- Cetuximab (IND#103444) in Patients with Stage IIIA/IIIB Non-Small Cell Lung Cancer Keywords: Lung cancer, Radiation, Chemotherapy | RTOG 0630: A PHASE II TRIAL OF IMAGE GUIDED PREOPERATIVE RADIOTHERAPY FOR PRIMARY SOFT TISSUE SARCOMAS OF THE EXTREMITY Keywords: Soft Tissue Cancer, Preoperative Radiotherapy, Sarcomas | The Use of Wisconsin Ginseng (panax quinquefolius) to Improve Cancer-Related Fatigue: A Randomized, Double-Blind, Placebo-Controlled Phase III Study Keywords: Ginseng, Fatigue, Cancer | UFPTI 0609-PC01: A Study Using Photon/Proton Beam Radiation Therapy and Chemotherapy for Unresectable Carcinoma of the Pancreas Keywords: Pancreatic Cancer, Photon therapy, Proton therapy, radiation | UFPTI 0704-PC02: A Pilot Study Using Neoadjuvant Proton Beam Radiation Therapy and Chemotherapy for Marginally Resectable Carcinoma of the Pancreas Keywords: Pancreatic Cancer | UFPTI 0803-SA02: A Pilot Study Investigating Neoadjuvant Temozolomide-based Proton Chemoradiotherapy for High-Risk Soft Tissue Sarcomas Keywords: Soft Tissue Cancer, Sarcomas, Proton Chemoradiotherapy | UFPTI 1013-PC03: A Phase II Trial of Postoperative Proton Radiotherapy with Concomitant Chemotherapy for Patients with Resected Pancreatic Adenocarcinoma Keywords: Pancreatic Cancer, Proton radiation therapy, post-operative | Vaginal DHEA for Vaginal Symptoms: A Phase III Randomized, Double Blind, Placebo-Controlled Trial (N10C1) Keywords: DHEA, vaginal dryness, vaginal pain, cancer |
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